Since April 1, 2016, North York General Hospital has replaced the First Trimester Screening (FTS) test with an improved test called Enhanced FTS. This test adds two additional markers: placental growth factor (PlGF) and AFP to the current markers PAPP-A, beta-hCG and NT.
Enhanced FTS has a higher detection rate and a lower false positive rate for Down syndrome. Therefore, patients will have access to a test in the first trimester whose performance approaches that of IPS.
No action is needed on your part. When ordering FTS for your patient, the laboratory will automatically perform Enhanced FTS.
We would also like to take this opportunity to remind you of the SOGC guidelines regarding screening for fetal neural tube defects (October 2014): “The primary use of MS-AFP for the screening of open/closed neural tube defects screening should be discontinued with the limited clinical exceptions of pregnant women with a BMI >35 kg/m2 or when geographical or clinical access factors limit timely and good quality ultrasound screening at 18-22 weeks.”
For more information on Enhanced FTS please see our Frequently Asked Questions for singleton pregnancies
or for twin pregnancies
. Questions and queries can be directed to the Maternal Serum Screening Coordinator at 416-756-6653.
North York General Hospital, General site
4001 Leslie Street, 3rd floor